S&P 500 Healthcare Sector SEC Filings — August 05, 2026

USA S&P 500 Healthcare

By Gunpowder Editorial ·

5 high priority 3 medium priority 8 total filings analysed

Executive Summary

The S&P 500 Healthcare sector is experiencing a bifurcated growth story, with GLP-1 leaders Eli Lilly and Amgen driving strong revenue expansion, while CVS Health shows a dramatic earnings recovery from a low base.

Eli Lilly's Q2 2026 revenue surged 48% YoY, driven by Mounjaro and Zepbound, but EPS growth was significantly tempered by $3.03 per share in acquired IPR&D charges, creating a mixed signal. Amgen posted a 9.5% revenue increase and a 65.9% net income surge, benefiting from cost discipline. CVS Health raised full-year guidance after a 191.8% net income jump, though medical membership declined by 0.7 million. The most striking insider signal comes from Boston Scientific, where the CEO made a $9M open-market purchase, indicating strong conviction. AbbVie's 8-K filing was purely informational with no material data. Overall, the sector shows robust top-line growth but with rising R&D spending and regulatory headwinds from the IRA.

Materiality, sentiment, and priority are scored by Gunpowder’s analysis pipeline. How we score filings →

Filing types in this digest: 10-Q · 8-K · Form 4

Tracking the trend? Catch up on the prior S&P 500 Healthcare Sector SEC Filings digest from August 04, 2026.

Investment Signals (10)

  • Eli Lilly (BULLISH)

    Revenue grew 48% YoY to $23.0B, driven by Mounjaro (+91.2%) and Zepbound (+45.8%), with non-GAAP gross margin improving 130 bps to 86.3%

  • Amgen (BULLISH)

    Net income surged 65.9% YoY to $2.375B, with diluted EPS up 65% to $4.37, while cost of sales declined 6.6% YoY, showing strong operational leverage

  • GAAP diluted EPS nearly tripled to $2.31 (up from $0.80), and full-year Adjusted EPS guidance raised to $7.90-$8.10, signaling a strong turnaround

  • CEO Mahoney Michael F bought $9M of stock at $48.33, a massive insider purchase indicating strong confidence in the company's prospects

  • Eli Lilly (BULLISH)

    Cash from operations improved sharply to $16.02B for H1 2026 from $4.75B a year ago, a 237% increase, providing ample firepower for R&D and M&A

  • Health Care Benefits segment MBR improved 250 bps YoY to 87.4%, and prior years' health care costs developed favorably by $1.2B, indicating better underwriting

  • Amgen (BULLISH)

    Cash and cash equivalents rose to $13.989B from $9.129B at year-end 2025, a 53% increase, strengthening the balance sheet for potential acquisitions

  • Non-GAAP EPS guidance kept essentially flat at $35.50-$36.50 despite raised revenue guidance, as the $2.78 midpoint increase from business was fully offset by $3.03 in IPR&D charges

  • Director Habiger David C bought $50.1K of stock at $48.07, a smaller but still positive insider signal alongside the CEO's purchase

  • Days claims payable decreased 1.2 days QoQ to 41.7 days, potentially indicating faster claims processing or a shift in mix

Risk Flags (9)

  • Eli Lilly [HIGH RISK]

    Acquired IPR&D charges surged to $2.78B in Q2 2026 (vs $154M in Q2 2025), fully offsetting underlying business improvements and raising questions about M&A discipline

  • Eli Lilly [HIGH RISK]

    Outside the U.S., realized prices declined 36% primarily due to Mounjaro's addition to the NRDL in China, signaling pricing pressure in key international markets

  • CVS Health [MODERATE RISK]

    Medical membership declined by 0.7 million to 26.0 million, indicating competitive losses in the health insurance segment

  • Amgen [HIGH RISK]

    Faces headwinds from IRA-related provisions and a July MFN Letter, which could pressure drug pricing and margins in coming quarters

  • Eli Lilly [MODERATE RISK]

    Verzenio revenue declined 1.0% YoY, and Trulicity grew only 11.7% in Q2, suggesting potential competitive pressure or market saturation in these franchises

  • CVS Health [LOW RISK]

    Other comprehensive income swung from a gain of $213M in Q2 2025 to a loss of $13M in Q2 2026, indicating potential volatility in investment portfolio or hedging activities

  • Eli Lilly [MODERATE RISK]

    Long-term debt increased to $47.86B from $40.87B, and short-term borrowings rose to $7.05B from $1.64B, increasing financial leverage

  • Amgen [LOW RISK]

    Other income swung to a loss of $73M from a $394M loss in the prior year quarter, though the improvement is notable, the continued loss is a drag on earnings

  • CVS Health [LOW RISK]

    Total assets remained nearly flat at $253.8B, suggesting limited balance sheet growth despite revenue expansion

Opportunities (9)

  • Boston Scientific (OPPORTUNITY)

    CEO's $9M open-market purchase at $48.33 is a strong vote of confidence; the stock may be undervalued relative to management's view

  • Eli Lilly (OPPORTUNITY)

    Mounjaro revenue grew 91.2% YoY to $9.94B, and Zepbound grew 45.8% to $4.93B; continued volume growth in GLP-1s provides a multi-year growth runway

  • CVS Health (OPPORTUNITY)

    With Adjusted EPS guidance raised to $7.90-$8.10 and cash flow from operations guided to at least $11.5B, the stock offers a potential value play with strong cash generation

  • Amgen (OPPORTUNITY)

    With a 65.9% net income surge and cost of sales declining 6.6% YoY, the company is demonstrating operational efficiency that could drive further margin expansion

  • Eli Lilly (OPPORTUNITY)

    Non-GAAP gross margin improved 130 bps to 86.3%, and with raised revenue guidance of $85.0-$87.0B, the core business is exceptionally strong despite one-time charges

  • CVS Health (OPPORTUNITY)

    The Health Care Benefits segment MBR improved 250 bps YoY to 87.4%, and favorable prior-year development of $1.2B suggests underwriting improvements are sustainable

  • Amgen (OPPORTUNITY)

    Cash and cash equivalents rose 53% to $13.989B, providing significant dry powder for bolt-on acquisitions or share buybacks

  • Eli Lilly (OPPORTUNITY)

    H1 2026 cash from operations of $16.02B (up 237% YoY) provides ample capacity to fund the $5.26B in property and equipment investments for manufacturing expansion

  • Boston Scientific (OPPORTUNITY)

    Director Habiger's purchase alongside the CEO's $9M buy creates a cluster of insider buying, often a precursor to positive catalysts

Sector Themes (6)

  • GLP-1 Dominance Driving Divergent Growth

    Eli Lilly's 48% revenue growth and Amgen's 9.5% growth highlight the GLP-1 class as the primary growth engine, while CVS Health's 7.3% growth reflects a more mature healthcare services model. The gap between pharma and services is widening.

  • Rising R&D and M&A Costs Weighing on EPS

    Eli Lilly's $3.03 per share in IPR&D charges and Amgen's continued IRA headwinds show that while top-line growth is strong, bottom-line benefits are being partially offset by increased investment and regulatory costs.

  • Insider Buying Signals Management Conviction

    Boston Scientific's CEO $9M purchase and director $57K purchase stand out as a strong bullish signal in a sector where insider buying has been sparse. This could indicate a perceived undervaluation.

  • Insurance Underwriting Cycle Turning Favorable

    CVS Health's MBR improvement of 250 bps and $1.2B in favorable prior-year development suggest the health insurance underwriting cycle is improving, which could benefit other managed care companies.

  • Cash Flow Generation Improving Dramatically

    Eli Lilly's H1 cash from operations surged 237% to $16.02B, and CVS Health guided to at least $11.5B in operating cash flow, indicating strong cash generation across the sector that could support dividends, buybacks, and M&A.

  • International Pricing Pressure Emerging

    Eli Lilly's 36% decline in realized prices outside the U.S. due to China's NRDL inclusion is a warning sign for other companies with international exposure, particularly in price-controlled markets.

Watch List (7)

  • Q3 2026 earnings call to assess whether IPR&D charges moderate and if Mounjaro/Zepbound volume growth continues; watch for any guidance revision on non-GAAP EPS [Ongoing]

  • 👁

    Impact of IRA provisions and July MFN Letter on drug pricing; Q3 2026 results will show if cost of sales decline is sustainable [Next earnings: likely Oct 2026]

  • Medical membership trends and MBR trajectory; watch for any further decline in membership or deterioration in underwriting margins [Next earnings: likely Nov 2026]

  • CEO's $9M insider purchase is a strong signal; watch for any upcoming product approvals or earnings beats that could validate the insider buying [Next earnings: likely Oct 2026]

  • International pricing dynamics, especially in China and Europe; further price declines could pressure international revenue growth [Ongoing]

  • 👁

    The 8-K filing was informational with no material data; watch for any subsequent filings that may provide business updates or guidance [Ongoing]

  • Sector-wide
    👁

    Impact of IRA drug price negotiations on Amgen and other companies with Medicare exposure; watch for any legislative developments [Ongoing]

Filing Analyses (8)
AMGEN INC 10-Q positive materiality 8/10

05-08-2026

Amgen reported strong Q2 2026 results with total revenues of $10,054M, up 9.5% YoY from $9,179M, driven by product sales growth of 8.7% to $9,537M. Net income surged 65.9% to $2,375M from $1,432M, with diluted EPS up to $4.37 from $2.65. However, cost of sales declined 6.6% YoY, and the company continues to face headwinds from IRA-related provisions and a July MFN Letter, while other income swung to a loss of $73M from a $394M loss in the prior year quarter.

  • · Total assets increased to $95,639M as of June 30, 2026 from $90,586M at December 31, 2025
  • · Cash and cash equivalents rose to $13,989M from $9,129M at year-end 2025
  • · Long-term debt increased to $51,859M from $50,005M at year-end 2025
  • · Accumulated deficit improved to $(22,275)M from $(25,107)M at year-end 2025
  • · Dividends declared of $2.52 per share in H1 2026, totaling $1,362M
  • · Other comprehensive income improved to $139M in H1 2026 from a loss of $478M in H1 2025
  • · The company faces regulatory and pricing headwinds including the July MFN Letter and IRA-related provisions
  • · R&D expenses increased 7.1% YoY in Q2 2026 to $1,868M, reflecting continued investment in later-stage clinical programs
CVS HEALTH Corp 8-K positive materiality 9/10

05-08-2026

CVS Health reported strong Q2 2026 results with total revenues of $106.1B, up 7.3% YoY, and GAAP diluted EPS of $2.31 (up from $0.80) and Adjusted EPS of $2.58 (up from $1.81). The company raised full-year 2026 guidance for GAAP diluted EPS to $6.84-$7.04, Adjusted EPS to $7.90-$8.10, and cash flow from operations to at least $11.5B. However, medical membership declined by 0.7 million to 26.0 million, and the company noted continued elevated cost trends and potential macro headwinds, maintaining a cautious outlook for the remainder of the year.

  • · Days claims payable were 41.7 days as of June 30, 2026, a decrease of 1.2 days compared to March 31, 2026.
  • · Prior years' health care costs payable estimates developed favorably by $1.2 billion during the six months ended June 30, 2026.
  • · Health Care Benefits segment MBR improved to 87.4% from 89.9% in Q2 2025.
  • · Health Services segment pharmacy claims processed remained essentially flat YoY at 473.0 million (30-day equivalent basis).
  • · Pharmacy & Consumer Wellness segment total revenues increased only slightly (0.7%) YoY due to regulatory-related price reductions, generic drug introductions, and pharmacy reimbursement pressure.
  • · The company maintained a cautious view for the remainder of the year due to continued elevated cost trends and potential macro headwinds.
  • · Medical membership declined by 0.7 million YoY to 26.0 million, partly due to the exit of the individual exchange business in 2026.
  • · Cash and cash equivalents increased to $11.3 billion from $8.5 billion at year-end 2025.
  • · Total assets were $253.8 billion, essentially flat compared to $253.5 billion at year-end 2025.
  • · Long-term debt decreased to $59.5 billion from $60.5 billion at year-end 2025.
CVS HEALTH Corp 10-Q positive materiality 9/10

05-08-2026

CVS Health reported strong financial results for Q2 2026, with total revenues of $106,096M, up 7.3% YoY from $98,915M, and net income attributable to CVS Health of $2,979M, a 191.8% surge from $1,021M in Q2 2025. However, the company experienced a decline in other comprehensive income, which swung from a gain of $213M in Q2 2025 to a loss of $13M in Q2 2026, and operating expenses decreased only slightly by 1.5% YoY.

  • · Diluted EPS for Q2 2026 was $2.31, up from $0.80 in Q2 2025.
  • · Total assets remained nearly flat at $253,768M as of June 30, 2026 vs $253,538M at Dec 31, 2025.
  • · Long-term debt decreased to $59,452M from $60,502M at Dec 31, 2025.
  • · Cash and cash equivalents increased to $11,329M from $8,453M at Dec 31, 2025.
  • · Dividends paid in H1 2026 were $1,725M, slightly up from $1,706M in H1 2025.
  • · The company repurchased $146M of treasury shares in Q2 2026.
ELI LILLY & Co 8-K mixed materiality 9/10

05-08-2026

Eli Lilly reported Q2 2026 revenue of $23.0 billion, up 48% YoY, driven by Mounjaro and Zepbound volume. Reported EPS rose 26% to $7.94, while non-GAAP EPS increased 33% to $8.38. However, EPS growth was significantly tempered by $3.03 per share in acquired IPR&D charges from Q2 business development activity, compared to only $0.14 in the prior year. The company raised full-year revenue guidance to $85.0-$87.0 billion but kept non-GAAP EPS guidance essentially flat at $35.50-$36.50, as the $2.78 midpoint increase from underlying business was fully offset by the $3.03 IPR&D charge.

  • · Q2 2026 U.S. revenue increased 33% to $14.4B, while revenue outside the U.S. increased 80% to $8.6B.
  • · Outside the U.S., realized prices declined 36% primarily due to Mounjaro's addition to the NRDL in China.
  • · Gross margin as a percent of revenue improved to 85.8% (reported) and 86.3% (non-GAAP), up 1.5 and 1.3 percentage points respectively.
  • · R&D expenses increased 14% to $3.8B, and marketing, selling & administrative expenses increased 25% to $3.4B.
  • · Asset impairment, restructuring and other special charges were $703M in Q2 2026, primarily from acquisition-related costs for Kelonia and Centessa.
  • · The effective tax rate rose to 23.3% from 16.5% due to non-deductible IPR&D charges.
  • · Full-year 2026 revenue guidance raised to $85.0B-$87.0B (from $82B-$85B), but non-GAAP EPS guidance narrowed to $35.50-$36.50 (from $35.50-$37.00).
  • · Performance margin guidance raised to 49.0%-50.5% from 47.0%-48.5%.
  • · Retatrutide Phase 3 data package complete for obesity, obstructive sleep apnea, and knee osteoarthritis pain; BLA submission planned for Q1 2027.
  • · Completed acquisitions of Orna, Ajax, Centessa, and Kelonia in Q2; three additional acquisitions post-quarter to build infectious disease portfolio.
  • · Committed an additional $4.5B to expand Indiana manufacturing sites.
ELI LILLY & Co 10-Q mixed materiality 9/10

05-08-2026

Eli Lilly reported strong Q2 2026 results with revenue of $22.97B, up 47.7% YoY, driven by Mounjaro ($9.94B, +91.2%) and Zepbound ($4.93B, +45.8%). Net income rose 25.3% to $7.10B. However, acquired in-process R&D charges surged to $2.78B (vs $154M), and Verzenio revenue declined 1.0% YoY, while Trulicity grew only 11.7% in Q2. Cash from operations improved sharply to $16.02B for H1 2026 from $4.75B a year ago.

  • · Total assets grew to $142.28B at June 30, 2026 from $112.48B at Dec 31, 2025.
  • · Long-term debt increased to $47.86B from $40.87B, while short-term borrowings rose to $7.05B from $1.64B.
  • · H1 2026 net cash used for investing activities was $19.31B, including $9.81B for acquisitions and $5.26B for property and equipment.
  • · Dividends paid in H1 2026 were $3.09B, up from $2.69B in H1 2025.
  • · Share repurchases totaled $3.96B in H1 2026 vs $1.89B a year ago.
  • · Total equity increased to $33.88B from $26.54B at year-end 2025.
  • · U.S. revenue in Q2 2026 was $14.41B (62.7% of total), up from $10.81B in Q2 2025.
  • · Outside U.S. revenue in Q2 2026 was $8.56B, up from $4.74B, driven by Mounjaro international sales of $5.15B.
  • · Taltz revenue was essentially flat at $856M in Q2 2026 vs $848M in Q2 2025.
  • · Neuroscience revenue grew 24.7% to $429M in Q2 2026.
BOSTON SCIENTIFIC CORP 4 positive materiality 3/10

05-08-2026

Director Habiger David C bought 1,042 Common Stock at $48.07 (~$50.1K). Habiger David C holds 15,060 shares after the transaction.

  • · Director Habiger David C bought 1,042 Common Stock at $48.07 (~$50.1K)
  • · Director Habiger David C bought 140 Common Stock at $48.59 (~$6.8K)
BOSTON SCIENTIFIC CORP 4 positive materiality 9/10

05-08-2026

Chairman, President & CEO Mahoney Michael F bought 186,240 Common Stock at $48.33 (~$9M). Mahoney Michael F holds 22,119 shares after the transaction.

  • · Chairman, President & CEO Mahoney Michael F bought 186,240 Common Stock at $48.33 (~$9M)
  • · Chairman, President & CEO Mahoney Michael F acquired 22,119 Common Stock at $48.43 (~$1.07M)
AbbVie Inc. 8-K neutral materiality 1/10

05-08-2026

AbbVie Inc. filed an 8-K on August 5, 2026, reporting Items 8.01 (Other Events) and 9.01 (Financial Statements and Exhibits). The filing is informational with no specific financial metrics, transaction details, or guidance disclosed. No positive or negative performance data is provided, making the filing neutral in nature.

  • · Filing date: August 5, 2026
  • · AccNo: 0001104659-26-091269
  • · Size: 595 KB
  • · Items reported: 8.01 and 9.01

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